This server was created to allow any researcher with interest in GPCRs to obtain the most accurate structural and dynamic information for a given receptor. Here, you can generate a homology-based 3D model of your query GPCR sequence, and/or further equilibrate your GPCR structure with our all-atom Molecular Dynamics simulation protocol.
Afterwards you can log in to your account and create a new project from a GPCR sequence, or from an already existing GPCR structure (MD simulations project) or else continue working on your existing project.
If you use this server for your research, please cite the following references:
This project is part of our research in membrane receptors, and is currently funded by the Carl Trygger Foundation. We also appreciate the support from the Computational and Systems Biology program (ICM, Uppsala University) and the Swedish strategic research programme eSSENCE. For more information, follow the links to know more about us and about the GPCR-ModSim project.
Happy GPCR modeling!